Key takeaways: Antibiotics only work against bacteria. Colds, flu, most coughs, bronchiolitis, and most sore throats and diarrhea are caused by viruses, and antibiotics won’t help. Babies do need antibiotics for bacterial infections like UTIs, some ear infections, pneumonia, and serious infections. Give the full course as prescribed, and ask your doctor before stopping.
Antibiotics are important medicines, but they’re not right for every illness.
When Antibiotics Help
- Urinary tract infections.
- Bacterial pneumonia.
- Many ear infections, especially in babies under 6 months or with severe symptoms.
- Strep throat (uncommon in babies).
- Skin infections like impetigo or cellulitis.
- Serious infections like meningitis or bloodstream infections.
When They Don’t Help
- Colds and runny noses, even with green mucus.
- Flu (antiviral medicine is different).
- Bronchiolitis.
- Most coughs.
- Most viral diarrhea.
From the author
From First Breath to First Birthday is my month-by-month guide to your baby’s first year, written as a NICU and postpartum nurse. My book covers common first-year illnesses and the warning signs that mean it’s time to call the doctor, explained the way I’d explain them at the bedside.
Ear Infections
The AAP guideline allows “watchful waiting” for some older babies and children (6 months and older) with mild ear infections, with follow-up, because many get better on their own. Babies under 6 months with ear infections are usually treated with antibiotics.
Why Overuse Is Harmful
- Side effects: diarrhea, rash, yeast infections, and allergic reactions.
- Antibiotic resistance: bacteria can become harder to treat.
- Effects on gut bacteria.
Giving Antibiotics Correctly
- Use an oral syringe marked in milliliters.
- Give the full course, unless your doctor tells you to stop.
- Store as directed. Some need refrigeration.
- Don’t use leftover antibiotics or share them.
Side Effects to Watch For
- Diarrhea: common; call if severe or bloody.
- Diaper rash or thrush.
- Rash or hives: call your doctor.
Call 911 if your baby has: trouble breathing, swelling of the face or lips, or hives with vomiting after a dose.
The Bottom Line
Antibiotics treat bacteria, not viruses. Trust your doctor’s judgment, give the full course when prescribed, and watch for side effects.
Want more support for your baby’s first year? My book, From First Breath to First Birthday, is available on Amazon.
Related Articles
Sources
- Centers for Disease Control and Prevention. Antibiotic use: be antibiotics aware. https://www.cdc.gov/antibiotic-use
- Lieberthal AS, Carroll AE, Chonmaitree T, et al. The diagnosis and management of acute otitis media. Pediatrics. 2013;131(3):e964-e999.
- American Academy of Pediatrics. Antibiotics: when they can and can’t help. HealthyChildren.org. https://www.healthychildren.org
This article is for general education and is not a substitute for individualized medical advice. Always talk with your baby’s health care provider or your own provider about your specific situation. If you think your baby or you may have a medical emergency, call 911.

